Peptide Evidence Rankings

Last updated: 2026-05-07. 51 compounds ranked by clinical evidence strength.

Rank	Compound	Evidence Level	Studies Indexed	Category	FDA Approved
1	Cagrilintide	Very Strong	20	Metabolic	No
2	DSIP	Very Strong	20	Sleep Peptide	No
3	Kisspeptin-10	Very Strong	20	Reproductive Peptide	No
4	Semaglutide	Very Strong	20	GLP-1 Agonist	Yes
5	Tesamorelin	Very Strong	20	GHRH Analog	Yes
6	Tirzepatide	Very Strong	20	Dual Agonist (GLP-1/GIP)	Yes
7	KPV	Very Strong	19	Anti-Inflammatory	No
8	PT-141	Very Strong	19	Melanocortin Agonist	Yes
9	Epitalon	Strong	30	Telomerase Activator	No
10	GHRP-2	Strong	20	GHRP	No
11	Glutathione	Strong	20	Antioxidant	No
12	MK-677	Strong	20	GH Secretagogue (Oral)	No
13	NAD+	Strong	20	Longevity	No
14	Retatrutide	Strong	20	Triple Agonist (GLP-1/GIP/Glucagon)	No
15	Sermorelin	Strong	20	GHRH Analog	No
16	Thymosin Alpha-1	Strong	20	Immune Peptide	No
17	Tesofensine	Strong	20	Small Molecule	No
18	Gonadorelin	Strong	2	GnRH Analog	Yes
19	Larazotide	Strong	2	Zonulin Antagonist	No
20	IGF-1 LR3	Moderate-Strong	20	Growth Factor	No
21	Semax	Moderate-Strong	20	Cognitive Peptide	No
22	CJC-1295	Moderate	20	GHRH Analog	No
23	GHK-Cu	Moderate	20	Copper Peptide	No
24	GHRP-6	Moderate	20	GHRP	No
25	Ipamorelin	Moderate	20	GHRP	No
26	LL-37	Moderate	20	Antimicrobial Peptide	No
27	Melanotan II	Moderate	20	Melanocortin Agonist	No
28	MOTS-c	Moderate	20	Mitochondrial Peptide	No
29	Selank	Moderate	20	Anxiolytic Peptide	No
30	SS-31	Moderate	20	Mitochondrial Peptide	No
31	AOD-9604	Moderate	18	GH Fragment	No
32	TB-500	Moderate	15	Thymosin Beta-4 Fragment	No
33	Follistatin-344	Moderate	9	Myostatin Inhibitor	No
34	Hexarelin	Moderate	4	GHRP	No
35	ARA-290	Moderate	3	EPO Receptor Agonist	No
36	Oxytocin	Moderate	2	Neuropeptide	No
37	Argireline	Moderate	1	Cosmetic Peptide	No
38	OS-01	Moderate	1	Cosmetic Peptide	No
39	BPC-157	Emerging	20	Body Protective Compound	No
40	Humanin	Emerging	3	Mitochondrial Peptide	No
41	VIP	Emerging	2	Neuropeptide	No
42	Thymalin	Emerging	2	Thymic Peptide	No
43	Klotho	Emerging	2	Anti-Aging Protein	No
44	5-Amino-1MQ	Preclinical	2	NNMT Inhibitor	No
45	PE-22-28	Preclinical	2	Nootropic Peptide	No
46	Pinealon	Preclinical	2	Khavinson Peptide	No
47	Cortagen	Preclinical	2	Khavinson Peptide	No
48	Dihexa	Preclinical	2	Neurotropic Peptide	No
49	FGL Loop	Preclinical	2	Neurotropic Peptide	No
50	FOXO4-DRI	Preclinical	1	Senolytic Peptide	No
51	Synapsin	Preclinical	1	Nootropic Peptide	No

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Evidence Dashboard.

Name: Peptide Clinical Evidence Rankings — PeptiDex
Creator: PeptiDex
License: https://creativecommons.org/licenses/by/4.0/

All 51 peptides ranked by strength of clinical evidence. Horizontal bars represent relative study count. Click any row to view full details.

Compounds: 51

Total Studies: 668

FDA Approved: 5

↻Last updated: May 2026

Compounds

Total Studies

668

FDA Approved

Strong+ Evidence

Cite this dataset

PeptiDex Editorial Team. (2026). Peptide Clinical Evidence Rankings. PeptiDex. https://peptidex.app/tools/evidence

CC-BY 4.0

Very Strong

Strong

Moderate-Strong

Moderate

Emerging

Preclinical

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