Pinealon
Last reviewed June 3, 2026
Also known as: EDR peptide, Glu-Asp-Arg
Quick Answer
Pinealon is a khavinson peptide research compound (not FDA-approved for human use) studied for neuroprotection. Pinealon is a tiny tripeptide from Russian bioregulatory research that crosses into brain cells and modulates their gene expression, studied for neuroprotection and cognitive longevity. Research dose: 5–10 mg daily x 10 days. Half-life: not established. Available from COA-verified vendors with code PEPTIDEX for up to 20% off.
Where to Source
Ranked by $/mg1Bio Longevity Labs Best $/mg
$59.47
$69.97Save $10.50
20mg vial
$3.50/mg
99%+ purityTested May 2026
Use code for 15% off:
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Rankings independent · Research use only
Synthetic tripeptide (Glu-Asp-Arg) bioregulatory peptide developed by Khavinson's St. Petersburg Institute. Acts as a penetrating peptide that crosses the blood-brain barrier and enters neuronal cell
Where to Buy Pinealon
COA-verified vendors · Use code PEPTIDEX for up to 20% off
* Prices for research peptide acquisition. Not therapeutic products.
| Vendor | Purity | List Price | With PEPTIDEX | Code | Shop |
|---|---|---|---|---|---|
Bio Longevity LabsTriple-Tested | 99%+ | $69.9720 mg | $59.47Save 15% | PEPTIDEX | * Research vendor — verify your regional regulations before purchase. Shop |
Bio Longevity LabsTriple-Tested
$69.97 · 20 mg$59.47−15%
Use code PEPTIDEX for 15% off at Bio Longevity Labs.
* Research vendor — verify your regional regulations before purchase.
Shop at Bio Longevity Labs§ Mechanism of Action
Synthetic tripeptide (Glu-Asp-Arg) bioregulatory peptide developed by Khavinson's St. Petersburg Institute. Acts as a penetrating peptide that crosses the blood-brain barrier and enters neuronal cell nuclei. Modulates gene expression in brain tissue, upregulates antioxidant enzymes (catalase, superoxide dismutase), promotes neuroprotection, and supports the pineal gland's circadian regulation. Shown to reduce hypoxia-induced neuronal damage.
§ Primary Benefits
- 1Neuroprotection
- 2cognitive enhancement
- 3antioxidant
- 4circadian rhythm support
§ Clinical Evidence
Pinealon increases resistance of neuronal cells to hypoxia
Khavinson et al.: Pinealon treatment increased resistance of human neuroblastoma cells to hypoxia, upregulating catalase and superoxide dismutase expression and reducing oxidative damage.
PreclinicalPeptide regulation of aging via epigenetic mechanisms
Khavinson et al.: Review documenting the epigenetic mechanisms by which short Khavinson peptides including Pinealon modulate histone acetylation and gene expression in brain tissue to slow aging.
Preclinical§ Safety Profile
Based on Russian bioregulatory research. Limited Western RCT validation. Generally considered safe in published use. Not FDA-approved. Research only. Caution: Khavinson research base has limited independent Western reproducibility.
See our evidence grading methodology for how we evaluate and grade peptide safety data.
§ Dosing Protocol
* Dosing data from published literature — not a human use recommendation.
RouteSubQ
Dose Range5000–10000 mcg
FrequencyDaily x 10 days
Cycle Length1–1 weeks
Khavinson protocol: 5–10mg per course. Intranasal administration also studied. No validated Western dosing.
§ Expected Outcomes
Week 1
Neuroprotection markers in preclinical models
Month 2–3
Cognitive and circadian rhythm support in published cohort studies
§ Adverse Effects
| Side Effect | Incidence | Severity |
|---|---|---|
Injection site reaction | Rare | mild |
Where to Source Pinealon for Research
Finding verified, high-purity Pinealon requires rigorous COA verification. We independently evaluate vendors based on third-party HPLC testing, purity thresholds (≥98%), and batch-specific documentation.
View COA-Verified Pinealon✓ Third-party tested·✓ US shipping·✓ COA on every batch
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Cite This Page
⚠️ Educational only · Not medical advice · For research use only. Information on this page is compiled from peer-reviewed literature and is intended strictly for educational and informational purposes. Peptides discussed may be unapproved research chemicals — consult a licensed healthcare professional before considering any peptide compound. Read our full disclaimer
Affiliate disclosure: PeptiDex may earn commissions from purchases made through vendor links on this page. This does not affect our editorial ranking or vendor recommendations — we exclusively feature vendors that pass independent COA verification. See our methodology · Editorial policy
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